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Illustrated Articles

Medications & Supplements

  • Cyclosporine ophthalmic ointment is an immunosuppressant used in the treatment of eye diseases suspected to be immune-related, including keratoconjunctivitis sicca (KCS) and other inflammatory conditions of the eye. Cyclosporine comes as an ophthalmic ointment but may sometimes be compounded into a higher concentration ophthalmic solution for pets not responding to the ointment. It is important to remember that it may take days to weeks to notice improvement. Do not stop giving the medication without asking your veterinarian. If signs of serious side effects or immune suppression occur, contact your veterinarian immediately.

  • Cyclosporine is given by mouth and is used to treat atopic dermatitis in dogs and cats. It has also been used off-label to treat other types of immune-mediated conditions. Give as directed. The most common side effects include stomach upset, such as vomiting, diarrhea, and decreased appetite. Do not use in pets with severe infections, a history of cancer, allergies to the medication, that are nursing or pregnant, or in pets younger than six months old. If a negative reaction occurs, contact your veterinarian.

  • Cyproheptadine is given by mouth and is used off label to treat allergic skin conditions, certain toxicities, and to stimulate appetite. Give as directed by your veterinarian. Common side effects include sleepiness, increased appetite, and dry mouth. Do not use in pets that are allergic to it or pets undergoing skin allergy testing within the next two weeks. If a negative reaction occurs, please call your veterinary office.

  • Cytarabine is a chemotherapy medication commonly used off label to treat blood cancers and brain inflammation. It is an injectable solution usually given in the vein by a veterinary professional. Common side effects include gastrointestinal upset and low blood cell counts. This medication should not be used or used with caution in pets with liver or kidney disease, those that have an allergy to this medication, and pregnant/lactating pets. If a negative reaction occurs, call your veterinary office.

  • Dantrolene is a muscle relaxant used to help relax the urinary tract and improve urine flow in cats and dogs. It has also been used to help prevent muscle contractions caused by certain toxicities in dogs and malignant hyperthermia in miniature pigs and dogs. It is used off label (extra label) in veterinary medicine. Dantrolene comes in capsule and injectable forms.

  • Darbepoetin alfa is prescribed off label to treat low red blood cell levels (anemia) caused by progressing kidney disease in dogs and cats. It is administered by injections under the skin.

  • Decoquinate is given by mouth and is used off label in dogs to prevent coccidia infections. Side effects are uncommon. Do not use in animals that are allergic to it or to treat coccidia infections (only use as a preventive).

  • Topical deltamethrin/deltamethrin combination products (brand names PetArmor®, Sentry®, Zodiac®, others) are synthetic pyrethroid insecticides used to repel mosquitoes and kill fleas and ticks on dogs older than 12 weeks of age for up to 6 months. Products may be also used to repel and kill sandflies. Never use in cats or aquatic species. Deltamethrin/deltamethrin combination products come in an impregnated collar form.

  • Deracoxib (brand name Deramaxx) is a non-steroidal anti-inflammatory drug (NSAID) used in dogs after surgery to reduce the pain associated with surgery (e.g., orthopedic and dental surgeries), as well as for the treatment of osteoarthritis. This article discusses possible side effects, risk factors, drug interactions, monitoring, and proper storage.

  • Deslorelin (brand name Suprelorin-F®) is a synthetic hormonal agent used to manage adrenocortical disease in ferrets. Deslorelin has also been used as a temporary contraceptive in intact male dogs or ferrets, to suppress estrus in small mammals, to decrease reproductive behavior in pet birds, and to induce ovulation in horses. Caution when handling if pregnant or child-bearing age.